objective(s): with the advent of nanotechnology, significant progress has been made in the area of nanoscale materials such as nanosilver (ag-nps). these nanoparticles have a wide range of applications and been used for antimicrobial purposes for more than a century. however, little attention has been paid to the toxicity of nanosilver wound dressing. this study was designed to investigate the ...

background t-2 toxin is a mycotoxin, exposure to which causes dermal and systemic toxicity. crataegus pontica (a member of the rosaceous family) is a small tree with caduceus foliage that is widely distributed throughout the western and central areas of iran. objectives this study was performed to examine the healing effects of creams prepared using crataegus pontica leaf extract on dermal toxi...

silver salts and nanosilver (ns) are the common antimicrobial used in the treatment of chronic wounds, so they are important to assess their dermal toxicity. therefore, in this study, the possible dermal toxicity of ns particles and silver nitrate (agno3), was tested by determining the serum level of transforming growth factor-β1(tgf-β1) and study on of mouse skin tissue. in this study, 30 balb...

objective(s): nanosilver is one of the most widely used nanomaterials due to its strong antimicrobial activity. thus, because of increasing potential for exposure of human to nanosilver, there is an increasing concern about possible side effects of these nanoparticles. in this study, we tested the potential dermal toxicity of nanosilver bandage on serum chemical biomarkers in mice.  materials a...

Explanation.................................................................................................... 161 Evaluation for acceptable daily intake .......................................................... 161 Biochemical aspects ................................................................................ 162 Absorption, distribution and excretion ......................................

Comparative Toxicity of Seventeen Pesticides to the Quelea, House Sparrow, and Red-Winged Blackbird. SCHAFER, E. W., JR., BRUNTON, R. B., LOCKYER, N. F. AND DE GRAZIO, J. W. (1973). Toxicol. Appl. Phurmacol. 26, 154-157. The acute po LD5,, values of 17 commercial or experimental pesticides were determined for quelea (Quelea quelea), house sparrows (Passer domesticus), and red-winged blackbirds ...

Explanation ..................................................................................................... 227 Evaluation for acceptable daily intake ............................................................ 228 1. Biochemical aspects .......................................................................... 228 1.1 Absorption, distribution and excretion .................................

Explanation.................................................................................................... 203 Evaluation for acceptable daily intake .......................................................... 204 Biochemical aspects ................................................................................ 204 Absorption, distribution and excretion ......................................

Regulatory information requirements for pesticides call for submission of acute systemic toxicity data for up to three different exposure routes (oral, dermal, inhalation) for both active ingredients and formulated products. Similar multi-route testing is required in the European Union and elsewhere for industrial chemicals. To determine the value of acute toxicity testing by more than one rout...

Objective(s): Silver nanoparticles have been widely used as new potent antimicrobial agents in cosmetic and hygienic products, as well as in new medical devices. Serious concerns have been expressed on the potential health risks of dermal applications of nanosilver containing consumer products (AgNPs), therefore regulatory health risk assessment has become necessary for the saf...